It is important to make an informed decision with your doctor about which adrenaline device is right for you. Allergy & Anaphylaxis Australia have created this adrenaline comparison to show the similarities and differences of adrenaline devices in Australia.
Anapen®
EpiPen®
neffy®
How do I give the adrenaline device?
Anapen®
Injection in mid thigh
EpiPen®
Injection in mid thigh
neffy®
Spray in nose
Does the adrenaline device contain a needle?
Anapen®
Yes
EpiPen®
Yes
neffy®
No
Does each adrenaline device contain only one dose?
Anapen®
Yes
EpiPen®
Yes
neffy®
Yes
What doses are available?
Anapen®
500ug
EpiPen®
150ug or 300ug
neffy®
1mg or 2mg
What are the weight and age ranges?
Anapen®
More than 50kg: 500ug
EpiPen®
7.5kg-20kg: 150ug
More than 20kg: 300ug
neffy®
4 years and over
15 kg to less than 30kg: 1mg
30kg and over: 2mg
Is the adrenaline device available in Australia?
Anapen®
No because of a supply shortage. Hopefully will be available soon
EpiPen®
Yes
neffy®
Yes on private prescription only from February 2026
Helpful saying to remember how to give
Anapen®
White end on leg; press thumb on red
EpiPen®
Blue to the sky, orange to the thigh
neffy®
Place neffy® in the nose, press and up it goes
Is the adrenaline device available on PBS (Pharmaceutical Benefits Scheme)?
Anapen®
Yes – when supply is available
EpiPen®
Yes
neffy®
No – this may change in future
What is the cost to buy on PBS?
Anapen®
2 devices for the price of one prescription which is currently $25 or $7.70 for concession card holders
EpiPen®
2 devices for the price of one prescription which is currently $25 or $7.70 for concession card holders
neffy®
Not available
Is the adrenaline device available to buy over the counter (OTC)?
Anapen®
Yes – when supply available
EpiPen®
Yes
neffy®
No – this may change in future
What is the cost OTC?
Anapen®
$80 – $120 for one
EpiPen®
$80 – $120 for one
neffy®
Not available
How do I store the adrenaline device?
Anapen®
Room temperature between 15 and 25°C most of the time.
Do not store in fridge. Do not freeze.
Out of direct light.
EpiPen®
Room temperature between 15 and 25°C most of the time.
Do not store in fridge. Do not freeze.
Out of direct light.
neffy®
Room temperature below 25°C. neffy ® can be exposed to high temperatures up to 50°C for short periods. Please contact CSL Medical Information 1800 642 865 for further information.
Do not store in the fridge as there’s a risk it may accidentally freeze.
There are no special requirements to protect neffy® from direct sunlight. However, care should be taken to store neffy® where the temperature stays below 25°C.
Can the adrenaline device be used if frozen?
Anapen®
No.
Low temperatures can damage injector device mechanisms.
EpiPen®
No.
Low temperatures can damage injector device mechanisms.
neffy®
If accidentally frozen, the device will not spray. It cannot be used if the contents are frozen. Allow neffy® to thaw for at least one hour at room temperature. Do not use unless completely thawed.
If someone is experiencing anaphylaxis and neffy® is frozen, use another adrenaline device if available. Do not wait for neffy® to thaw before treating anaphylaxis.
Freezing does not affect its shelf life.
Expiry date from when made overseas
Anapen®
12 – 18 months
EpiPen®
12 – 18 months
neffy®
1mg – 24 months
2mg – 30 months
What is the size of the adrenaline device?
Anapen®
17.5cm x 2.0cm x 2.0cm
EpiPen®
15cm x 2.7cm x 2.0cm
neffy®
6.3cm x 4.3cm x 2.2cm
Does it come with a case?
Anapen®
No, but you can ask the pharmacist for a case for free – the case is reusable
EpiPen®
Yes – a clear case
EpiPen® case has a yellow lid
EpiPen®Jnr case has a green lid
neffy®
No. You can buy a carry case (RRP*$17.95) that holds 2 neffy® devices, if they have been removed from their blister package. Instructions on how to give neffy® are in the case
Can a used adrenaline device fit in the case?
Anapen®
Yes, used Anapen® with exposed needle will fit in case
EpiPen®
No, used EpiPen® is too long to fit back in case, but once used, the needle shield protects the needle
neffy®
Yes
Where do I find instructions on how to give the adrenaline device?
Anapen®
Device: Yes
Case: Yes via QR
ASCIA Action Plans/First Aid Plans for Anaphylaxis
EpiPen®
Device: Yes
Case: No
ASCIA Action Plans/First Aid Plans for Anaphylaxis
neffy®
Device: No
Case: Yes – insert in the case
Also found:
- on neffy box
- on blister pack
ASCIA Action Plans/First Aid Plans for Anaphylaxis
Does using trainer device feel like using the real device?
Anapen®
Yes
EpiPen®
Similar, but real device has a stronger spring
neffy®
No – must push upwards HARD on the real device but the trainer is easy to push
Learn more about adrenaline and adrenaline devices
Adrenaline devices
Learn about how adrenaline works and how to store and use adrenaline devices.
Anapen®
Learn about Anapen®, how adrenaline works, how to use Anapen® and more.
EpiPen®
Learn about EpiPen®, how adrenaline works, how to use EpiPen® and more.
neffy®
Learn about neffy®, how adrenaline works, how to use neffy® and more.
Frequently asked questions (FAQ)
Using an adrenaline device FAQ
Allergy & Anaphylaxis Australia answers common questions about using an adrenaline (epinephrine) devices such as Anapen® or EpiPen®.
Buying an adrenaline device FAQ
Allergy & Anaphylaxis Australia answers common questions about buying an adrenaline (epinephrine) device such as Anapen® or EpiPen®.
neffy® FAQ
Allergy & Anaphylaxis Australia answers questions about the device, safety and efficacy, cost, availability and more.
Preparing for an emergency
Learn more about preparing for a severe allergic reaction (anaphylaxis) and what to expect if you or a loved one experiences anaphylaxis.