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Anapen®

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What is Anapen®?  

Anapen® is an adrenaline injector device which contains the medication adrenaline (epinephrine).  

ADRENALINE IS LIFE SAVING medication for someone experiencing a severe allergic reaction (anaphylaxis). 

Adrenaline is the first line emergency treatment for anaphylaxis. Adrenaline devices are designed to be used by anyone in an emergency. 

Adrenaline is a natural hormone made by our bodies but in anaphylaxis, our body cannot make and release enough adrenaline to reverse the potentially life-threatening allergic reaction. For this reason, we need to give more adrenaline through a device such as Anapen®. 

An Anapen® contains one dose of adrenaline. 

What doses are available for Anapen®? 

The dose of Anapen® is worked out by weight. In Australia, Anapen® is currently only available in a 500-microgram dose, which is suitable for someone over 50kg. Weight guidelines for adrenaline devices can be found on the bottom of the ASCIA Action Plan for Anaphylaxis. 

Anapen® 500

Contains adrenaline (epinephrine) dose of 500 micrograms/0.3mL

Anapen® Junior 150 and Anapen® 300 are no longer available in Australia.

Anapen® 500 is currently out of stock in Australia due to changes in how Anapen® is supplied internationally.

How is Anapen® packaged?

Each Anapen® you receive from the pharmacy will be in a cardboard box. Each cardboard box contains one Anapen®. If you buy two Anapen®s, you will get two boxes. 

Inside this box is a clear plastic insert containing the Anapen®. Remove the Anapen® from the plastic insert. Once the Anapen® is removed from the plastic insert, it is ready to be used. 

Anapen® does not come with a case. However, you can ask your pharmacist to give you a case when you get your Anapen®. They are free. The same case should be used each time you replace your Anapen.  

Used Anapen®s will fit in the case.  

What does Anapen® look like? 

On the Anapen® you will see:

  • Instructions for use
  • An expiry date  
  • A viewing window (lens) to check if the solution inside is still clear. If the solution becomes dark, cloudy or has specks floating in it, the Anapen® should be replaced. However, if this is the only device available it should be used. 
  • After the Anapen® has been used, the needle can be seen and the injection indicator changes from white to red

Anapen® before it has been used.

Anapen® after it has been used. Note the needle is exposed.

An empty Anapen® case.

The case containing an Anapen®.

How to give Anapen® 

Instructions on how to give an Anapen® can be found  

  • on the ASCIA Action Plan for Anaphylaxis for Anapen®
  • on the Anapen® 
  • via QR code on the end of the Anapen® case 
  • via QR code on the ASCIA Action Plan/First Aid Plan which takes you to the ASCIA website where there are instructions on how to use Anapen® 

Follow the 4 steps below: 

PULL OFF BLACK NEEDLE SHIELD

PULL OFF GREY SAFETY CAP from red button

PLACE NEEDLE END FIRMLY against outer mid-thigh at 90° angle (with or without clothing)

PRESS RED BUTTON so it clicks and hold for 3 seconds. REMOVE Anapen®

How to give an Anapen®

Remember: White end on leg; press thumb on red

For more videos about anaphylaxis management, visit our resources page.

Anapen® is given into the outer mid-thigh

There is a large muscle in the outer mid-thigh. Injecting adrenaline into this muscle helps get the adrenaline to the rest of the body quickly. The adrenaline device can be given through clothing. 

Remember:  hold the leg still if you are giving an adrenaline device to someone else as they may move unexpectantly. 

When the Anapen® has been used, the needle is exposed and there is a risk of needle stick injury (accidently pricking yourself or someone else with the needle). To avoid this, the Anapen® should be placed back into the case (needle end first) after use. Keep your fingers away from the needle end. 

If no case is available:  

  • Place into a hard plastic container, such as a lunchbox  
  • Recap the needle carefully by placing the needle shield, wide end up, on a flat surface and then placing the needle end of the device into the wider end of the needle shield (see instructions below under Anapen® trainer information)

There is a risk of needle stick injury when placing the used device back into the needle shield, however, if no hard plastic container or Anapen® carry case are available, place the needle end of the device into the wider end of the needle shield as stated above.

How to store an Anapen® 

Anapen®s should be stored or kept: 

At room temperature between 15 and 25°C most of the time. Do not store in the fridge. Do not freeze. 

Out of direct light

In an unlocked, easy to get to place (out of reach of small children)

Anapen® expiry dates 

Anapen® usually expires 12 to 18 months from when it is made overseas.

The expiry date can be found on the Anapen® box and on the Anapen®s .

Expired Anapen®s do not work as well as in-date devices and should not be relied on to treat anaphylaxis. However, an expired  Anapen® should still be given if it is the only adrenaline device available. 

Make a note of when your Anapen®s are due to expire and book an appointment for a new prescription with your health professional. 

If you use your Anapen® make sure you replace it as soon as possible.

Anapen® Trainer devices 

It is important to know how to give an Anapen® in an emergency. Using an Anapen® trainer is a great way to do this. The Anapen® trainer contains no needle or medication and can be reused (unlike the actual Anapen® used in an emergency which contains only one dose of adrenaline and cannot be reused). 

If your child is at risk of anaphylaxis, practiscing with them could help you think about how you may need to hold them if you had to give Anapen® in an emergency. It may also help the child understand what would happen if they had anaphylaxis. 

It is important to store the Anapen® trainer away from the real Anapen®. You can mark the Anapen®  trainer with tape or a sticker to highlight that it is not the real Anapen® containing adrenaline and a needle. 

Unless the Anapen® trainer is reset in the correct way it can easily become jammed and will not be able to be used. 

Frequently asked questions (FAQ)

Using an adrenaline device FAQ

Allergy & Anaphylaxis Australia answers common questions about using an adrenaline (epinephrine) devices such as Anapen® or EpiPen®. 

Buying an adrenaline device FAQ

Allergy & Anaphylaxis Australia answers common questions about buying an adrenaline (epinephrine) device such as Anapen® or EpiPen®. 

Learn more about adrenaline and adrenaline device

Adrenaline devices

Learn about how adrenaline works and how to store and use adrenaline devices like Anapen® and EpiPen®.

EpiPen®

Learn about EpiPen®, how adrenaline works, how to use EpiPen® and more.

Preparing for an emergency

Learn more about preparing for a severe allergic reaction (anaphylaxis) and what to expect if you or a loved one experiences anaphylaxis.